Polymorphisms of BIRC5 Gene is Associated with Chronic HBV Infection in Iranian Population
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چکیده
منابع مشابه
GATA3 Gene Polymorphisms Associated with Allergic Rhinitis in an Iranian Population
Background: The development of allergic rhinitis (AR) is caused by the interaction between genetic predisposition and environmental factors. In this study, the association between GATA3 single nucleotide polymorphisms and AR in an Iranian population was identified. Methods: This case-control study was performed on 86 patients with AR and 86 healthy subjects. This study aimed to e...
متن کاملpolymorphisms within the promoter region of the gamma interferon (ifn-γ) receptor1 gene are associated with the susceptibility to chronic hbv infection in an iranian population
background chronic hepatitis b virus (hbv) infection is a multifactorial disease that can result in serious clinical complications. host genetic background especially the genes that encode immunologic factors like inf-γ and its receptor (ifn-γ r) are critical in the pathogenesis of infection. materials and methods genomic dna from peripheral blood samples of 200 chronically hbv infected patient...
متن کاملPolymorphisms within the Promoter Region of the Gamma Interferon (IFN-γ) Receptor1 Gene are Associated with the Susceptibility to Chronic HBV Infection in an Iranian Population
BACKGROUND chronic hepatitis B virus (HBV) infection is a multifactorial disease that can result in serious clinical complications. Host genetic background especially the genes that encode immunologic factors like INF-γ and its receptor (IFN-γ R) are critical in the pathogenesis of infection. OBJECTIVES The current study aimed to investigate the association between two single nucleotide polym...
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PURPOSE The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are associated with HBV outcomes. MATERIALS AND METHODS IL28B genetic variations (rs12979860) were genotyped by pyrosequencing of DNA samples from 137 individuals with chronic HBV infection [50 inactive...
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Background and Aims: Engagement of the receptor for advanced glycation end products (RAGE) and its ligand “S100A12 protein” induce a cascade of reactions that eventually might lead to develop an inflammatory response dependent on NF-κB. Although involvement of S100A12 and RAGE in some autoimmune disease have proved, in chronic hepatitis B (CHB) infection functions of the prote...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2019
ISSN: 0970-1915,0974-0422
DOI: 10.1007/s12291-018-0805-3